Expert Pharmacy Insights

Progesterone for Luteal Phase Support: Why the Route Changes Everything

Vaginal progesterone gives serum levels that look low while putting roughly eight times more hormone into the endometrium than an injection does, and raising the dose does not raise the blood level. Route by route dosing, the endometrial versus serum numbers, what 26,198 randomised women showed about choosing between injection and vaginal, and why dydrogesterone will not show on a progesterone test.