Antibiotics Articles
Evidence-based articles about antibiotics from certified pharmacists
Amoxicillin and Clavulanate Dosage: Why Two 250 mg Tablets Are Not One 500 mg
A 625 mg co-amoxiclav tablet is 500 mg amoxicillin plus 125 mg clavulanate, and every common strength carries the same 125 mg of clavulanate. That is why two 375 mg tablets are not one 750 mg dose, and why the label forbids certain substitutions.
Azithromycin Dosage: Why a Five Day Course Keeps Working After You Stop
Azithromycin has a serum half life near 70 hours, so a five day course keeps working long after the last tablet. Labelled doses by infection, the trial data showing three and five day courses give comparable total exposure, and the QT warning that decides who should avoid it.
Nitrofurantoin for UTI: Dosing, and Why It Fails Above the Bladder
Nitrofurantoin concentrates in urine and barely reaches anything else, which makes it excellent for cystitis and useless for a kidney infection. Labelled dosing, why every dose needs food, and the pulmonary reaction that appears after six months of suppressive therapy.
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