Sleep Health Articles
Evidence-based articles about sleep health from certified pharmacists
Modafinil vs Armodafinil: Dose, Half Life and Side Effect Data Compared
Armodafinil is the R half of modafinil, which is why 50 mg of it matches 100 mg of modafinil on the concentration curve and 200 mg produces about 70 percent more total exposure. This guide covers the label dose equivalence, the pooled side effect tables for each drug with placebo subtraction, the dose response data, and the contraceptive failure interaction that both carry.
Zopiclone vs Eszopiclone: Same Molecule, Different Doses and Different Countries
Eszopiclone is the active half of the zopiclone molecule, which is why 3 mg of one is described the same way as 7.5 mg of the other. This guide covers the dose conversion, which country licenses which drug, the FDA dose stratified side effect tables, the shared boxed warning on complex sleep behaviours, and what the comparative evidence actually shows.
Zopiclone Dosage and Duration: 3.75 mg, 7.5 mg and the Limits That Matter
Zopiclone has only two licensed strengths, 7.5 mg for adults and 3.75 mg for older adults and anyone with liver or kidney impairment. This guide covers the licensed dosing, the four week duration limit, what the network meta-analysis evidence shows against other sleep medicines, and a week by week reduction plan based on the 2025 European deprescribing consensus.
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