Expert Pharmacy Insights

Dapsone Gel (Aczone) 5% vs 7.5%: How to Use It, Results, Side Effects, Warnings and Cost

Dapsone gel (Aczone) is a prescription acne gel in two strengths: 5% twice daily and 7.5% once daily. This guide covers how to apply each, who it is approved for, what the four label trials showed against vehicle, side effects with label rates, the methemoglobinemia and G6PD warnings, the orange staining with benzoyl peroxide, pregnancy and breastfeeding, generic approvals and what US pharmacies pay per gram.