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Cenforce D

Generic: Sildenafil/Dapoxetine

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About Cenforce D

Cenforce D is a combination tablet made in India by Centurion Laboratories, the maker of Cenforce. Each tablet contains sildenafil 100 mg for erectile dysfunction and dapoxetine 60 mg for premature ejaculation. We sell it in packs of 80, 120 and 160 tablets, from $1.09 a tablet in the largest pack.

The "D" is dapoxetine, a second medicine for a different condition, not a stronger form of Cenforce. This page sets out what that second medicine adds and costs, who should and should not take the combination, how to take it, and the price per tablet. Clinical figures come from the US Viagra label, the European Priligy (dapoxetine) product information and published trials, listed at the end.

Cenforce D at a glance

Active ingredientsSildenafil 100 mg (as citrate) and dapoxetine 60 mg per tablet
Brand and makerCenforce D, by Centurion Laboratories Pvt Ltd, Vadodara, Gujarat, India
TreatsErectile dysfunction and premature ejaculation in the same man
Regulatory statusNot approved by the FDA, MHRA, EMA, TGA or Health Canada. India approved sildenafil with dapoxetine tablets in 2020 for men aged 18 to 64 with both conditions.
Where the doses sitSildenafil 100 mg is the labelled maximum (usual dose 50 mg). Dapoxetine 60 mg is the maximum; the Priligy label says to start at 30 mg.
When to take itAbout an hour before sex; one tablet in 24 hours at most; no alcohol
Packs80, 120 and 160 tablets
Price per tablet$1.36 (80 pack) down to $1.09 (160 pack), before shipping
Delivery7 to 14 business days to the US, UK, Australia and Canada; $25 shipping under $149, free from $149

Price per tablet

Prices below are as of October 2026. The pack selector above always shows the current price.

PackPricePer tabletShippingPer tablet with shipping
80 tablets$109$1.36$25$1.68
120 tablets$155$1.29Free$1.29
160 tablets$175$1.09Free$1.09

The 120 pack costs less per tablet than the 80 pack even before shipping ($1.29 against $1.36), and it ships free, while the 80 pack works out at $1.68 a tablet with $25 shipping. Super Kamagra holds the same two doses at $1.98 to $2.17 a tablet. Even the smallest pack is 80 tablets, which is a lot for a dapoxetine dose that no one should start on (see below).

Cenforce D or Cenforce 100?

Both contain 100 mg of sildenafil. What Cenforce D adds is dapoxetine, a short-acting SSRI that delays ejaculation. It does nothing for erections, and erection problems are listed among its own common side effects.

Cenforce 100Cenforce D
Sildenafil100 mg100 mg
DapoxetineNone60 mg
TreatsErectile dysfunctionErectile dysfunction and premature ejaculation
AlcoholKeep it moderateAvoid it
Added risksNone beyond sildenafilLow blood pressure on standing (the reason the Priligy label says not to use dapoxetine with sildenafil), fainting, nausea, dizziness, diarrhoea, insomnia, and dangerous interactions with antidepressants and other serotonin-acting medicines
Price per tablet$0.71 to $0.92$1.09 to $1.36

If your problem is getting or keeping an erection, Cenforce 100, or Cenforce 50 at the label's usual dose, is the right product. Some men with weak erections rush to finish before the erection fades; that looks like premature ejaculation but is an erection problem, and treating the erection may be enough.

Do you have premature ejaculation?

The Priligy product information limits dapoxetine to men with diagnosed premature ejaculation: ejaculation less than two minutes after penetration, happening with minimal stimulation and before the man wishes, in most attempts over the last six months, with poor control and marked distress or relationship difficulty. It says dapoxetine should not be used simply to delay ejaculation in men without that diagnosis. Our sildenafil and dapoxetine guide explains how the two conditions overlap.

What the dapoxetine label says about this combination

  • The European Priligy product information says dapoxetine should not be used in men taking PDE5 inhibitors such as sildenafil, because together they may cause a drop in blood pressure on standing (orthostatic hypotension).
  • It says the efficacy and safety of dapoxetine with a PDE5 inhibitor have not been established.
  • Sildenafil 100 mg raised dapoxetine exposure by 22% in its interaction study, which the label does not expect to matter clinically; the concern is the effect of the two together on blood pressure.
  • One trial offers some reassurance. In 495 men with both conditions who were already stable on a PDE5 inhibitor, adding dapoxetine at a flexible 30 or 60 mg dose for 12 weeks raised the average (arithmetic mean) time to ejaculation to 5.2 minutes against 3.4 minutes on placebo, with side effects in 29.6% against 20.0%.

That trial used separate tablets in men whose erections were already working on their PDE5 inhibitor. The product information was last revised in 2021, after this trial, and still says the combination's safety and efficacy have not been established. No trial has tested Cenforce D itself.

Why both halves are at the maximum dose

DrugLabel starting doseLabel maximumIn Cenforce D
Sildenafil50 mg (25 mg for some groups)100 mg100 mg
Dapoxetine30 mg for every patient60 mg60 mg

The Priligy product information says treatment should not be started with 60 mg; the dose goes up only if 30 mg did not work well enough without moderate or severe side effects or warning signs of fainting. In its 24 week placebo-controlled trial, the median average time to ejaculation was 1.91 minutes on 60 mg against 1.72 minutes on 30 mg (1.05 minutes on placebo). Across the phase 3 trials, nausea and dizziness were about twice as common on 60 mg. Men with both conditions who have not taken dapoxetine before should start with a 30 mg combination such as Suhagra Force 50 or DA Zeagra (sildenafil 50 mg with dapoxetine 30 mg). Our dapoxetine dosage guide has the details.

How to take Cenforce D

  1. Swallow one tablet whole with water about an hour before sex. Sildenafil works from about 30 minutes to 4 hours after a dose, and dapoxetine is taken 1 to 3 hours before sex.
  2. Take it on an empty stomach or after a light meal; a high-fat meal delays sildenafil's peak by about an hour.
  3. Do not drink alcohol. The Priligy product information warns that alcohol with dapoxetine can increase dizziness, drowsiness, slowed reflexes and impaired judgement, and may make fainting more likely.
  4. Do not take it with recreational drugs. Ecstasy (MDMA), ketamine or LSD can cause serotonin syndrome or heart rhythm problems with dapoxetine, and opioids or benzodiazepines add to drowsiness and dizziness.
  5. Avoid grapefruit and grapefruit juice for 24 hours before a dose. It raises dapoxetine levels.
  6. Take no more than one tablet in 24 hours, and never with any other erectile dysfunction treatment (tadalafil, vardenafil, avanafil or another sildenafil product) or another dapoxetine product. Dapoxetine is meant to be taken only when sex is planned, not every day, and the label asks a doctor to review whether it is worth continuing after the first four weeks or six doses.
  7. Remember that sildenafil needs sexual stimulation to work.

For sildenafil, the label advises considering a 25 mg starting dose for men over 65, with liver impairment or severe kidney impairment, or taking erythromycin or a strong CYP3A4 inhibitor; men on an alpha blocker should start at 25 mg once stable on it; men on ritonavir should take no more than 25 mg in 48 hours. For dapoxetine, moderate CYP3A4 inhibitors such as erythromycin, clarithromycin, fluconazole, verapamil and diltiazem limit the dose to 30 mg. Dapoxetine is not recommended in severe kidney impairment, and the label asks for caution at 60 mg in men known to be poor CYP2D6 metabolisers or taking a strong CYP2D6 inhibitor; a pharmacist can check your medicines. Cenforce D is the wrong product for all of these men.

Side effects

Each drug brings its own side effects, and headache is common to both. The sildenafil rates come from the fixed-dose trials in the sildenafil label; the dapoxetine rates come from its phase 3 trials, which the product information reports without matching placebo figures.

Drug and doseMost common side effects
Sildenafil 100 mgHeadache 28%, flushing 18%, indigestion 17%, abnormal vision (mostly a colour tinge) 11%, nasal congestion 9%
Placebo in the same trialsHeadache 7%, flushing 2%, indigestion 2%, abnormal vision 1%, nasal congestion 2%
Dapoxetine 60 mgNausea 22.2%, dizziness 10.9%, headache 8.8%, diarrhoea 6.9%, fatigue 4.1%, insomnia 3.9%
Dapoxetine 30 mg, for comparisonNausea 11.0%, dizziness 5.8%, headache 5.6%, diarrhoea 3.5%, fatigue 2.0%, insomnia 2.1%
Grouped bar chart of sildenafil side effects by fixed dose. Headache: placebo 7%, 25 mg 16%, 50 mg 21%, 100 mg 28%. Flushing: 2%, 10%, 19%, 18%. Indigestion: 2%, 3%, 9%, 17%. Abnormal vision: 1%, 1%, 2%, 11%. Nasal congestion: 2%, 4%, 4%, 9%.
Side effects by sildenafil dose in the fixed-dose trials behind the FDA label. Every Cenforce D tablet contains 100 mg. Source: Viagra prescribing information, section 6.1, Table 1.

Our dapoxetine side effects guide covers the dapoxetine data in full.

Fainting

Dapoxetine can cause fainting, sometimes with a very slow heartbeat. In the placebo-controlled phase 3 trials it happened in 0.06% of men on 30 mg and 0.23% on 60 mg, mostly within 3 hours of a dose and often after the first dose. Nausea, dizziness, light-headedness or sweating often came first, but fainting can also happen with no warning. If you notice these signs, lie down with your head low, or sit with your head between your knees, until they pass, and do not drive. Drink enough fluids, do not take it when dehydrated, and do not stand up quickly after lying or sitting for a long time.

Sildenafil also lowers blood pressure, and the dapoxetine label says dapoxetine should not be used with PDE5 inhibitors such as sildenafil because together they may cause a drop in blood pressure on standing. It asks doctors to check blood pressure and pulse lying and standing before the first dose.

When to get urgent help

  • Fainting, chest pain, or severe dizziness during or after sex.
  • An erection lasting more than 4 hours. Without prompt treatment it can permanently damage the penis and cause lasting erectile dysfunction.
  • Sudden loss or reduction of vision or hearing. Stop taking it and get medical help straight away.
  • Agitation, confusion, fever, sweating or muscle twitching after taking it with another serotonin-acting medicine or a recreational drug (possible serotonin syndrome).
  • A seizure. Stop taking it.
  • Swelling of the lips, tongue or throat, difficulty breathing or swallowing, or a rash, hives or blistering skin.
  • If you take more than one tablet, contact a doctor or emergency department straight away.

Tell emergency staff that you took sildenafil and dapoxetine, how much and when. Nitrates must not be given soon after sildenafil; the label says it is not known when they can safely be given, even 24 hours later.

Who must not take Cenforce D

  • Anyone using nitrates in any form, including poppers, or riociguat or vericiguat.
  • Anyone allergic to sildenafil, dapoxetine or any ingredient of the tablet.
  • Men with heart failure (NYHA class II to IV), heart conduction problems such as AV block or sick sinus syndrome, significant ischaemic heart disease or significant heart valve disease.
  • Men who have fainted before, or who have had dizziness, light-headedness or fainting on standing up. The Priligy product information says a doctor should check lying and standing blood pressure and pulse before the first dose, and that dapoxetine should be avoided after a documented or suspected reaction of this kind.
  • Men with a history of mania, hypomania, bipolar disorder, schizophrenia or severe depression, or with current depression. Do not stop an antidepressant in order to take this, and stop and see a doctor if low mood develops.
  • Men with epilepsy that is not well controlled.
  • Men taking antidepressants (SSRIs, SNRIs, tricyclics, MAOIs), thioridazine, or other serotonin-acting medicines such as triptans, tramadol, linezolid, lithium, L-tryptophan or St John's wort, or within 14 days of stopping one. Do not start one of these within 7 days of your last dose.
  • Men taking a strong CYP3A4 inhibitor such as ketoconazole, itraconazole, ritonavir, saquinavir, telithromycin, nefazodone, nelfinavir or atazanavir.
  • Men with moderate or severe liver impairment.
  • Men with blood pressure below 90/50, a recent heart attack or stroke, retinitis pigmentosa or another inherited retinal disorder, or previous vision loss in one eye from NAION (contraindications in the UK and EU sildenafil label).
  • Men for whom sex is inadvisable because of a heart condition.

Dapoxetine should not be used under 18 and is only indicated up to age 64. Talk to a doctor first if you have aortic stenosis, a deformed penis, a condition that raises the risk of prolonged erections, controlled epilepsy, raised eye pressure or a risk of angle-closure glaucoma, a bleeding disorder or an active stomach ulcer, or if you take warfarin or other blood thinners, antiplatelet medicines, aspirin or anti-inflammatory painkillers, or blood pressure medicines. Cenforce D does not protect against sexually transmitted infections.

Prescription and legal status

Sildenafil is a prescription medicine in the US, Australia and Canada, and in the UK apart from 50 mg pharmacy packs. Dapoxetine is licensed as Priligy, on prescription, in the UK and Australia. The FDA and Health Canada have not approved dapoxetine, and no sildenafil and dapoxetine combination is licensed by the FDA, MHRA, TGA or Health Canada; Cenforce D is not licensed in any of these countries. In the US, the FDA says personal importation of unapproved medicines is illegal in most circumstances. See a doctor before using it and check the rules where you live.

Buying genuine Cenforce D

The MHRA warns that any medicine not authorised for sale in the UK can be unsafe or ineffective, and that erectile dysfunction pills bought online may contain no active ingredient, the wrong dose, hidden drugs or toxic ingredients. That warning covers Cenforce D, which is not authorised in the UK, and the MHRA advises UK buyers to use UK-registered pharmacies. Check that each strip names Centurion Laboratories and shows both strengths, a batch number and an expiry date, and reject strips that are damaged, unsealed or unmarked. These checks cannot prove a product is genuine, because counterfeiters copy packaging. If a batch causes unusual symptoms, stop using it, seek medical advice, and report it to your medicines regulator (the MHRA Yellow Card scheme in the UK, FDA MedWatch in the US, the TGA in Australia or Health Canada) as well as to us.

Delivery

We ship Cenforce D to the US, UK, Australia and Canada in plain packaging with tracking. Standard delivery takes 7 to 14 business days to most countries. Shipping costs a flat $25 on orders under $149 and is free from $149. See our shipping page and refund policy.

Related guides

Other sildenafil and dapoxetine tablets: Super Kamagra, Super P-Force and Super Fildena.

Sources

  • Priligy (dapoxetine) 30 mg and 60 mg film-coated tablets, summary of product characteristics, sections 4.1 to 4.5, 4.8 and 5.1, revised June 2021. Swedish Medical Products Agency
  • PRILIGY dapoxetine 30 mg film-coated tablet, ARTG 147946. Therapeutic Goods Administration
  • VIAGRA (sildenafil citrate) US prescribing information, sections 2, 4, 5, 6.1 and 12. DailyMed
  • Viagra EPAR product information (EU), section 4.3. European Medicines Agency.
  • McMahon CG et al. Efficacy and safety of dapoxetine in men with premature ejaculation and concomitant erectile dysfunction treated with a phosphodiesterase type 5 inhibitor. J Sex Med 2013;10(9):2312-25. PMID 23845016.
  • Central Drugs Standard Control Organisation, India. Fixed dose combinations approved by DCG(I) in 2020, item 2 (10 February 2020).
  • MHRA. 20 million illegal erectile dysfunction pills seized as MHRA warns against risky online buys, 13 February 2026. GOV.UK.
  • US Food and Drug Administration. Personal Importation. FDA

This page is for information and is not medical advice. Sildenafil and dapoxetine are prescription medicines; speak to a doctor before using either, and before combining them.

Key Information

  • βœ“Active Ingredient: Sildenafil/Dapoxetine
  • βœ“Category: Men's Health
  • βœ“Form: tablet
  • βœ“Brand: test
  • βœ“Manufacturer: Centurion Laboratories

Frequently Asked Questions

What is Cenforce D?

Cenforce D is a tablet made in India by Centurion Laboratories that combines sildenafil 100 mg, for erectile dysfunction, with dapoxetine 60 mg, for premature ejaculation. It is not approved by the FDA, MHRA, EMA, TGA or Health Canada. India approved sildenafil with dapoxetine tablets in 2020 for men aged 18 to 64 with both conditions.

What does the D in Cenforce D mean?

The D stands for dapoxetine, a short-acting SSRI that delays ejaculation. It is a second medicine for a different condition, not a stronger form of sildenafil. The sildenafil dose is the same 100 mg as in Cenforce 100.

Should I take Cenforce D or Cenforce 100?

If your only problem is getting or keeping an erection, Cenforce 100, or Cenforce 50 at the label's usual dose, is the right choice. The dapoxetine in Cenforce D does nothing for erections and adds a drop in blood pressure on standing, fainting, nausea, dizziness, diarrhoea and insomnia, plus dangerous interactions with antidepressants and other serotonin-acting medicines. Cenforce D only makes sense if you also have diagnosed premature ejaculation.

How much does Cenforce D cost per tablet?

As of October 2026 it costs $1.36 a tablet in the 80 pack, $1.29 in the 120 pack and $1.09 in the 160 pack, before shipping. Shipping is $25 under $149, so the 80 pack works out at $1.68 a tablet; the 120 and 160 packs ship free.

How do I take Cenforce D?

Swallow one tablet whole with water about an hour before sex, on an empty stomach or after a light meal. Take no more than one tablet in 24 hours, do not drink alcohol or take recreational drugs with it, avoid grapefruit juice for 24 hours before, and never combine it with another erection or dapoxetine product. Sildenafil needs sexual stimulation to work.

Is 60 mg of dapoxetine a starting dose?

No. The Priligy product information says every patient should start at 30 mg and that treatment should not be started with 60 mg. Men with both conditions who have not taken dapoxetine before should start with a 30 mg combination such as Suhagra Force 50 or DA Zeagra.

Is it safe to combine sildenafil and dapoxetine?

Not according to its label. The European Priligy product information says dapoxetine should not be used in men taking PDE5 inhibitors such as sildenafil, because together they may cause a drop in blood pressure on standing, and that the efficacy and safety of the combination have not been established. A 12 week trial in 495 men already stable on a PDE5 inhibitor, using separate tablets, found that adding dapoxetine helped, with side effects in 29.6% against 20.0% on placebo.

What are the side effects of Cenforce D?

Sildenafil 100 mg commonly causes headache (28%), flushing (18%), indigestion (17%) and abnormal vision, mostly a colour tinge (11%). Dapoxetine 60 mg commonly causes nausea (22.2%), dizziness (10.9%), headache (8.8%) and diarrhoea (6.9%). Dapoxetine can also cause fainting, mostly within 3 hours of a dose and sometimes without warning.

Who must not take Cenforce D?

Anyone using nitrates or poppers, riociguat or vericiguat, or allergic to either drug; men with heart failure, heart conduction problems, significant heart disease, a history of fainting or of dizziness on standing, mania, bipolar disorder, depression, schizophrenia, or epilepsy that is not controlled; men taking antidepressants or other serotonin-acting medicines, or strong CYP3A4 inhibitors; men with moderate or severe liver disease; men with blood pressure below 90/50, a recent heart attack or stroke, retinitis pigmentosa or past NAION; and men under 18. Dapoxetine is only indicated up to age 64.

Do I need a prescription for Cenforce D?

Yes, for both drugs. Sildenafil is a prescription medicine in the US, Australia and Canada, and in the UK apart from 50 mg pharmacy packs. Dapoxetine is prescription-only where it is licensed, such as the UK and Australia, and is not approved by the FDA or Health Canada. No regulator in these countries has licensed a sildenafil and dapoxetine combination. See a doctor before using it and check the rules where you live.

How long does delivery take?

We ship to the US, UK, Australia and Canada in plain packaging with tracking. Standard delivery takes 7 to 14 business days. Shipping is a flat $25 on orders under $149 and free from $149.

Medical References

  1. 1.ClinicalTrials.gov NCT01063855

Sources: U.S. National Library of Medicine (DailyMed, PubMed), openFDA

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