
Omez 20mg
Generic: Omeprazole
Select pack size
60 capsules · $0.32 per capsule
About Omez 20mg
Omez 20 is Dr Reddy's Indian brand of omeprazole 20 mg, a proton pump inhibitor (PPI) that lowers the amount of acid the stomach makes. It is a capsule: Tata 1mg, PharmEasy, Truemeds and Apollo Pharmacy all list Omez 20 as a capsule from Dr Reddy's Laboratories Ltd, sold in India in strips of 20 capsules (PharmEasy, Truemeds, Apollo) or 30 capsules (Tata 1mg, Apollo). We sell Omez 20mg in packs of 60, 90 and 120 capsules, from $0.31 a capsule in the larger packs before shipping.
Three points before you order. First, price, plainly: omeprazole 20 mg is one of the cheapest medicines in the US. US pharmacies pay about 3 cents a capsule for generic omeprazole 20 mg capsules, and omeprazole 20 mg is sold without a prescription for frequent heartburn in the US, the UK (small packs), Canada and Australia (small packs). If you live in the US, a local prescription for generic omeprazole will usually cost you less than ours once shipping is added (our estimate from NADAC); we have not compared UK shelf prices. Second, for heartburn you treat yourself, the non-prescription labels allow a 14 day course; our smallest pack is 60 capsules, which is two months at one a day. Using omeprazole for longer than a short course is something to do with a doctor, because some risks rise with long-term use (details below). Third, the US label says never take it with rilpivirine (an HIV medicine), and the US label says avoid taking it with clopidogrel (a blood thinner). If you take clopidogrel, do not stop it; ask the doctor who prescribed it before taking omeprazole (our advice). The doses and warnings below come from the US omeprazole delayed-release capsule label (made by Dr Reddy's for the US market), the UK omeprazole 20 mg gastro-resistant capsule label, the US and UK non-prescription labels, Health Canada and the Australian Poisons Standard, listed at the end.
Omez 20mg at a glance
| Active ingredient | Omeprazole 20 mg per capsule. Omeprazole blocks the acid pump (H+, K+ ATPase) in the stomach lining cells that make acid (UK label 5.1) |
| Brand and maker | Omez, Dr Reddy's Laboratories Ltd (Tata 1mg, PharmEasy, Truemeds, Apollo). PharmEasy gives a Baddi, Himachal Pradesh address; Apollo gives Dr Reddy's Hyderabad head office |
| Regulatory status | Omeprazole 20 mg is licensed in the US, UK, Australia and Canada, on prescription and in small non-prescription heartburn packs. This Indian Omez pack is not registered with the FDA, MHRA, TGA or Health Canada |
| Usual dose from the label | 20 mg once a day for most uses: heartburn and other reflux (GERD) symptoms for up to 4 weeks, healing of erosive oesophagitis over 4 to 8 weeks, and duodenal ulcer for 4 weeks (US label 2.1). Some uses need 40 mg or more, set by a doctor |
| Half-life | 0.5 to 1 hour in the blood in healthy people (US label 12.3). Even so, the UK label says it controls acid secretion "with once daily dosing" (5.1) |
| Packs | 60, 90 and 120 capsules. Indian strips hold 20 or 30 capsules (see above) |
| Price per capsule | $0.32 (60 pack) down to $0.31 (90 and 120 packs), before shipping |
| Delivery | 7 to 14 business days to the US, UK, Australia and Canada; $25 shipping under $149, free from $149 |
What omeprazole 20 mg is used for
The US label for omeprazole delayed-release capsules lists these uses (US label 1): short-term treatment of an active duodenal ulcer in adults; getting rid of H. pylori infection, together with antibiotics, in adults with a duodenal ulcer, to lower the risk of the ulcer coming back; short-term treatment (4 to 8 weeks) of an active benign stomach (gastric) ulcer in adults; heartburn and other symptoms of gastroesophageal reflux disease (GERD) for up to 4 weeks, from age 2; short-term treatment (4 to 8 weeks) of erosive esophagitis (EE) diagnosed by endoscopy, and keeping EE healed, from age 2; and long-term treatment of conditions where the stomach makes far too much acid, such as Zollinger-Ellison syndrome, in adults.
The UK label adds treating and preventing stomach and duodenal ulcers caused by NSAID painkillers, preventing them in people at risk (over 60, or with a past ulcer or upper gut bleeding), and preventing ulcers from coming back (UK label 4.1, 4.2).
The US non-prescription label covers one use only: frequent heartburn, meaning heartburn on 2 or more days a week, in adults 18 and over. It is "not intended for immediate relief of heartburn"; it "may take 1 to 4 days for full effect" (Prilosec OTC Drug Facts).
H. pylori treatment needs a test, antibiotics and a doctor. The label regimens combine omeprazole with clarithromycin and amoxicillin or other antibiotics (US label 2.1; UK label 4.2), and the UK label says antibiotic choice should follow local resistance patterns. Do not put together an H. pylori treatment yourself (our advice).
Price per capsule
Prices below are as of October 2026; the pack selector shows the current price.
| Pack | Price | Per capsule | Shipping | Per capsule with shipping |
|---|---|---|---|---|
| 60 capsules | $19 | $0.32 | $25 | $0.73 |
| 90 capsules | $28 | $0.31 | $25 | $0.59 |
| 120 capsules | $37 | $0.31 | $25 | $0.52 |
All three packs are under the $149 free shipping line, so a single pack carries $25 shipping, which more than doubles the cost of the 60 pack. Before shipping the price per capsule is almost the same in all three packs.
How long a pack lasts. At one 20 mg capsule a day, the packs last 60, 90 and 120 days (our arithmetic). That is far more than one non-prescription heartburn course (14 days in the US and UK labels) and more than the 4 week course the US label gives for reflux symptoms. Buy a large pack only if a doctor has told you to take omeprazole for months, and check that the expiry date on the strips covers that time.
Compared with US omeprazole
| Omez 20mg (ours, Indian pack) | US generic omeprazole 20 mg capsule (prescription) | US non-prescription omeprazole 20 mg (tablet or capsule) | |
|---|---|---|---|
| Maker | Dr Reddy's (India) | Many makers, including Dr Reddy's | Prilosec OTC (Procter and Gamble) and store brands |
| Prescription | Indian listings mark it prescription; the pack is not registered in the US | Yes ("Rx Only") | No; 14 day course, adults |
| Cost per unit | $0.31 to $0.32 before shipping | NADAC $0.03045 | NADAC $0.38889 to $0.47438 (tablets and capsules) |
| Cost of 60 | $19 before shipping, $44 with it | About $1.83 at NADAC | About $23 to $28 at NADAC |
NADAC is the average price US pharmacies pay to buy a medicine, published by the US Medicaid programme; it is not the shelf price. In the NADAC file of 28 October 2026, all 35 NDC rows for prescription omeprazole DR 20 mg capsules are at $0.03045 a capsule, including Dr Reddy's own US capsule (NDC 55111-644-01). Non-prescription rows are higher: omeprazole DR 20 mg tablets $0.39142 (19 rows), omeprazole magnesium 20 mg capsules $0.38889 (5 rows) and tablets $0.47438 (10 rows). All have an effective date of 21 October 2026. There is no NADAC row for Prilosec capsules, which are discontinued in the US (see below).
Say it plainly: US prescription generic omeprazole is far cheaper than ours. Our capsule costs about 10 times what US pharmacies pay for a generic omeprazole 20 mg capsule before our shipping, and about 17 to 24 times with it (our arithmetic). Before shipping, our price per capsule is a little below the NADAC rows for non-prescription omeprazole; with shipping it is higher. If you live in the US and need omeprazole for more than a 14 day heartburn course, a prescription for generic omeprazole will usually cost you less than ours. In the UK, small general sale packs cover a 14 day heartburn course; for longer use, see your GP (we have not compared UK shelf prices).
Is Omez the same as US omeprazole? It has the same active ingredient at the same strength. Dr Reddy's also makes the US generic omeprazole 20 mg capsule whose label we quote, but we have no document showing that Indian Omez 20 is made to the same formula, and we have not seen data comparing Omez 20 with Prilosec or any US, UK, Australian or Canadian product.
Which strength to choose
| Daily dose | With Omez | How it fits the labels |
|---|---|---|
| 10 mg once daily | Omez 10mg (also in our range) | US: keeping erosive oesophagitis healed in people with liver impairment or of Asian descent (2.1, 8.6, 8.7); children 10 to under 20 kg (2.2). UK: the recommended long-term dose after reflux oesophagitis has healed; some people with reflux symptoms respond to 10 mg (4.2) |
| 20 mg once daily | One capsule (this product) | US: duodenal ulcer, reflux symptoms, healing and keeping healed erosive oesophagitis (2.1); children 20 kg and over (2.2). UK: most uses, including NSAID ulcers (4.2). US and UK non-prescription heartburn dose |
| 20 mg twice daily | One capsule twice a day, with antibiotics | H. pylori regimens with two antibiotics: 10 days in the US triple therapy (2.1), one week in the UK regimens (4.2). Only as part of a course a doctor prescribes |
| 40 mg once daily | Two capsules | US: benign gastric ulcer, 4 to 8 weeks (2.1). UK: ulcers that respond poorly and severe oesophagitis (4.2). Only if your doctor sets this dose |
| 60 mg or more a day | Not a dose for this product | Zollinger-Ellison syndrome and similar conditions: starting dose 60 mg, adjusted by a specialist (US 2.1; UK 4.2) |
In a US placebo-controlled study of erosive oesophagitis, healing rates at week 8 were 74% on 20 mg, 75% on 40 mg and 14% on placebo, and "the 40 mg dose was not superior to the 20 mg dose" (US label 14.5). For reflux symptoms without oesophagitis, a Scandinavian study in the US label found complete relief of heartburn in 46% on 20 mg, 31% on 10 mg and 13% on placebo after up to 4 weeks (14.4). Taking more than your doctor set does not make it work faster (our advice).
How to take Omez 20mg
- Take it before a meal (US label 2.3). The UK label recommends taking it in the morning, swallowed whole with half a glass of water (4.2). Truemeds and Tata 1mg also say before a meal.
- Swallow the capsule whole; do not chew or crush it (US 2.3; UK 4.2). The pellets inside are coated so that stomach acid does not break down the omeprazole before it is absorbed (US 12.3).
- If you cannot swallow a capsule, the US label allows you to open it, empty all the pellets onto a tablespoon of soft, cool applesauce, and swallow the mixture straight away with a glass of cool water, without chewing or crushing the pellets and without saving any for later (US 2.3). The UK label also allows mixing the contents with a slightly acidic fluid such as fruit juice, or non-carbonated water, taken within 30 minutes (4.2). We have not confirmed that Omez 20 contains coated pellets, so check the capsule before trying this, and ask a pharmacist if you are unsure (our advice).
- If you miss a dose, take it as soon as you can; if the next dose is due, skip the missed one and take the next dose on time. "Do not take two doses at one time to make up for a missed dose" (US 2.3).
- Antacids may be taken with omeprazole (US 2.3).
How long to take it
Heartburn you treat yourself. The US non-prescription label says take one 20 mg tablet a day before eating in the morning for 14 days, "do not take more than 1 tablet a day", and "do not take for more than 14 days or more often than every 4 months unless directed by a doctor". The UK general sale capsules say up to 14 days, and "You must talk to a doctor if you do not feel better or if you feel worse after 14 days" (Boots One-a-day Acid Reflux Relief leaflet).
On a doctor's advice. The US label gives up to 4 weeks for reflux symptoms, 4 to 8 weeks to heal erosive oesophagitis (a further 4 weeks if it has not healed), and 4 weeks for a duodenal ulcer (2.1). For keeping oesophagitis healed, controlled studies "do not extend beyond 12 months" (1.6). The UK label says that if symptoms are not controlled after four weeks of 20 mg, "further investigation is recommended" (4.2), and that in all long-term treatment, especially beyond 1 year, patients "should be kept under regular surveillance" (4.4). The US Medication Guide says to take it "exactly as prescribed, at the lowest dose possible and for the shortest time needed".
If you have been taking omeprazole for months, talk to your doctor about whether you still need it and at what dose. Do not stop a course for an ulcer or H. pylori early without asking (our advice).
Lower doses for some groups
- Liver impairment. In people with any degree of liver impairment (Child-Pugh A, B or C), exposure to omeprazole is "substantially increased"; the US label recommends 10 mg once daily for keeping erosive oesophagitis healed (8.6). The UK label says 10 mg to 20 mg a day may be sufficient (4.2). For that maintenance use, Omez 20 is not suitable for someone with liver impairment; ask your doctor.
- People of Asian descent. In studies of healthy people, Asians had about four times the exposure of Caucasians, and the US label recommends 10 mg once daily for keeping erosive oesophagitis healed (8.7). For that use, Omez 20 is not suitable under the US label. The UK label does not mention this adjustment.
- Kidney impairment and older people. No dose adjustment is needed (UK 4.2; US 8.5 for older people).
- Children. The US label covers children aged 2 to 16 for reflux and oesophagitis, at 10 mg under 20 kg and 20 mg from 20 kg (2.2); the UK label covers children over 1 year and 10 kg (4.1). The US non-prescription label says children under 18 should ask a doctor, because "Heartburn in children may sometimes be caused by a serious condition". Give it to a child only on a doctor's advice.
Long-term use: what the labels warn about
Several of these warnings come from observational studies or case reports, and the labels apply them to PPIs as a group. Both labels tie several of them to long courses or high doses. Each item gives the label that says it.
- C. difficile diarrhoea. "Published observational studies suggest that PPI therapy like omeprazole may be associated with an increased risk of Clostridium difficile-associated diarrhea, especially in hospitalized patients" (US 5.3). The UK label says PPIs may lead to a "slightly increased risk" of gut infections such as Salmonella and Campylobacter and, in hospitalised patients, possibly C. difficile (4.4).
- Bone fractures. The US label says observational studies suggest a higher risk of fractures of the hip, wrist or spine, and that the risk was higher with high doses (multiple daily doses) and long-term use (a year or longer) (5.4). The UK label says PPIs, especially in high doses and over more than 1 year, "may modestly increase the risk of hip, wrist and spine fracture, predominantly in the elderly or in presence of other recognised risk factors", with observational studies suggesting an overall increase of 10% to 40%, some of it possibly due to other risk factors; people at risk of osteoporosis should get adequate vitamin D and calcium (4.4).
- Low magnesium. The US label says low magnesium "has been reported rarely" after at least three months on a PPI, in most cases after a year, and serious events include tetany, arrhythmias and seizures (5.9). The UK label calls it "Severe hypomagnesaemia" and says its signs "may begin insidiously and be overlooked" (4.4). For people on long treatment or taking digoxin or diuretics, the US label says doctors "may consider" checking magnesium before and during treatment; the UK label says they "should consider" it.
- Vitamin B12. Daily acid-lowering treatment over a long period (for example longer than 3 years) "may lead to malabsorption of cyanocobalamin (vitamin B-12)"; the US label calls reported deficiency rare (5.8). The UK label says this should be considered in people with low body stores or risk factors on long-term therapy (4.4).
- Fundic gland polyps. PPI use "is associated with an increased risk of fundic gland polyps that increases with long-term use, especially beyond one year"; most people had no symptoms and the polyps were found by chance at endoscopy (US 5.13). The UK label lists fundic gland polyps (benign) as common (4.8).
- Lupus. Cutaneous and systemic lupus erythematosus have been reported with PPIs, both new and as a flare of existing disease; the US label says "Avoid administration of PPIs for longer than medically indicated" (5.6).
- Kidney inflammation. Acute tubulointerstitial nephritis "may occur at any point during PPI therapy" (US 5.2); the UK label says it can progress to kidney failure (4.4).
- Hidden stomach cancer. Relief of symptoms "does not preclude the presence of gastric malignancy" (US 5.1). The UK label says that with alarm symptoms (unintended weight loss, repeated vomiting, trouble swallowing, vomiting blood or black stools) or a suspected gastric ulcer, cancer should be ruled out, "as treatment may alleviate symptoms and delay diagnosis" (4.4).
- Blood and urine tests. Omeprazole raises chromogranin A, which can give false results in tests for neuroendocrine tumours. The US label says stop omeprazole at least 14 days before the test (5.11); the UK label says at least 5 days, with a repeat 14 days after stopping if levels are still high (4.4). Tell the doctor ordering the test. The US label also notes false positive urine screening tests for cannabis (THC) in people taking PPIs (7).
Side effects
In worldwide clinical trials of omeprazole capsules (3,096 patients), the most common side effects (2% or more) were headache (7%), abdominal pain (5%), nausea (4%), diarrhoea (4%), vomiting (3%) and flatulence (3%). The label lists further reactions at 1% or more, including acid regurgitation, upper respiratory infection, constipation, dizziness and rash (each 2%) (US label 6.1). These are rates in people taking omeprazole; the label does not give placebo rates alongside them. Children aged 2 to 16 had more respiratory side effects (19%) (6.1).
The UK label lists side effects by frequency. Selected rows (UK label 4.8):
| Frequency | Side effects |
|---|---|
| Common (up to 1 in 10) | Headache; abdominal pain, constipation, diarrhoea, flatulence, nausea or vomiting; fundic gland polyps (benign) |
| Uncommon (up to 1 in 100) | Insomnia; dizziness, pins and needles, sleepiness; vertigo; raised liver enzymes; dermatitis, itching, rash, hives; fracture of the hip, wrist or spine; malaise, swelling of the ankles |
| Rare (up to 1 in 1,000) | Low white cells or platelets; allergic reactions such as fever, angioedema and anaphylaxis; low sodium; agitation, confusion, depression; taste changes; blurred vision; bronchospasm; dry mouth, mouth inflammation, gut thrush; hepatitis with or without jaundice; hair loss, sun sensitivity, AGEP and DRESS (serious skin reactions); joint and muscle pain; tubulointerstitial nephritis; more sweating |
| Very rare (up to 1 in 10,000) | Agranulocytosis, pancytopenia; aggression, hallucinations; liver failure, and brain effects (encephalopathy) in people with existing liver disease; erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis; muscle weakness; breast enlargement in men |
| Not known | Low magnesium (which may lead to low calcium and low potassium); microscopic colitis; subacute cutaneous lupus erythematosus |
The UK label says none of the listed reactions "was found to be dose-related" (4.8).
When to get urgent help
Call emergency services (911 in the US and Canada, 999 in the UK, 000 in Australia) or get medical help straight away if you have any of the following (our advice on urgency; what each label says is given in each point):
- Chest pain that could be your heart. The US non-prescription label says do not use it if you have heartburn with lightheadedness, sweating or dizziness, or chest or shoulder pain with shortness of breath, sweating, pain spreading to the arms, neck or shoulders, or lightheadedness: "These may be signs of a serious condition." The UK general sale leaflet says "Seek urgent medical attention" for chest pain with lightheadedness, sweating, dizziness or shoulder pain with shortness of breath, as it "could be a sign of a serious condition with your heart". Do not treat these symptoms as heartburn.
- Signs of bleeding or a serious stomach problem: vomiting blood, bloody or black stools, trouble or pain swallowing food, or unexplained weight loss (US non-prescription label; UK label 4.4).
- A serious allergic reaction: rash, face swelling, throat tightness or difficulty breathing (US Medication Guide). The US non-prescription label says stop use and seek medical help right away.
- A severe skin reaction: a rash that may blister, peel or bleed, including on the lips, eyes, mouth, nose, genitals, hands or feet, perhaps with fever, chills, body aches, shortness of breath or swollen lymph nodes. The US Medication Guide says stop taking it and call your doctor right away.
- Severe diarrhoea: watery stool, stomach pain and fever that does not go away; the US Medication Guide says call your doctor right away, as it may be C. difficile infection.
- Signs of a kidney problem: passing much less urine, or blood in the urine; the US Medication Guide says call your doctor right away.
- Signs of low magnesium: seizures, an abnormal or fast heartbeat, jitteriness, shaking, muscle spasms or cramps, spasm of the voice box; the US Medication Guide says tell your doctor right away. A seizure needs emergency care.
- Taking too much. The US label reports overdoses up to 2,400 mg with confusion, drowsiness, blurred vision, fast heartbeat, nausea, vomiting, sweating, flushing, headache and dry mouth; symptoms were transient and "no serious clinical outcome has been reported when omeprazole was taken alone" (US 10). If someone has taken a large amount, or other medicines as well, call Poison Control on 1-800-222-1222 in the US (US 10), or the Poisons Information Centre on 13 11 26 in Australia (our addition).
Tell the medical staff that you take omeprazole 20 mg, how much, when you last took it, and every other medicine you take.
Who should not take Omez 20mg
Never take it if:
- you have had an allergic reaction to omeprazole, to any ingredient of the capsule, or to any substituted benzimidazole (US label 4; UK label 4.3). The US Medication Guide adds an allergy to any other PPI medicine, and the UK general sale leaflet names pantoprazole, lansoprazole, rabeprazole and esomeprazole.
- you take a medicine containing rilpivirine, an HIV medicine (for example Edurant or Complera): PPIs, including omeprazole, "are contraindicated" (US label 4). The UK omeprazole label does not mention rilpivirine, but the UK rilpivirine (Edurant) label says rilpivirine "must not be used in combination with proton pump inhibitors" (Edurant SmPC 4.5, with PPIs listed under 4.3 Contraindications, emc). Ask your HIV doctor before any acid-lowering medicine.
- you take nelfinavir (an HIV medicine). The UK label says omeprazole "must not be used concomitantly with nelfinavir" (4.3); the US label says avoid the combination (7).
Avoid, or only with your doctor's agreement:
- Clopidogrel. The US label says "Avoid concomitant use of omeprazole with clopidogrel", because omeprazole reduces clopidogrel's activation, "even when administered 12 hours apart", and advises considering another antiplatelet (5.7). The UK label says the clinical relevance is uncertain, but "As a precaution, concomitant use of omeprazole and clopidogrel should be discouraged" (4.4). Never stop clopidogrel to take omeprazole; ask the doctor who prescribed the clopidogrel, who may choose a different acid medicine (our advice).
- Atazanavir (HIV): US: avoid (7). UK: "not recommended"; if judged unavoidable, close monitoring, a higher atazanavir dose with ritonavir, and "omeprazole 20 mg should not be exceeded" (4.4).
- St John's wort and rifampicin (rifampin): they "can substantially decrease omeprazole concentrations"; the US label says avoid them (5.10). The UK label says they may lower omeprazole levels (4.5).
- Posaconazole and erlotinib: the UK label says avoid the combination; omeprazole also significantly reduces the absorption of ketoconazole and itraconazole (UK 4.5).
- High-dose methotrexate: PPIs may raise and prolong methotrexate levels; a temporary break from omeprazole "may be considered" (US 5.12; UK 4.5). Low-dose weekly methotrexate users should still tell their doctor (our advice).
Medicines that may need monitoring or a dose change (US label 7 unless stated): warfarin (check INR; higher INR may lead to abnormal bleeding); citalopram (limit to 20 mg a day because of QT prolongation); cilostazol (reduce to 50 mg twice daily); phenytoin (monitor levels; the UK label says during the first two weeks); diazepam (watch for more sedation); digoxin (monitor; UK 4.5: caution with high omeprazole doses in older people); tacrolimus (monitor levels); mycophenolate mofetil (caution in transplant patients); saquinavir; and medicines that need stomach acid to be absorbed, such as iron salts, dasatinib and nilotinib. The US non-prescription label says ask a doctor or pharmacist first if you take any prescription medicine.
Pregnancy and breastfeeding. The US label says available data "fail to demonstrate an increased risk of major congenital malformations or other adverse pregnancy outcomes with first trimester omeprazole use" (8.1). The UK label says "Omeprazole can be used during pregnancy" and that it passes into breast milk but "is not likely to influence the child when therapeutic doses are used" (4.6). The US label says limited data suggest it may be present in milk and the benefits of breastfeeding should be weighed with the mother's need (8.2). The US non-prescription label says ask a health professional before use. Talk to your doctor or midwife first (our advice).
Ingredients. We have not confirmed Omez 20's inactive ingredients. Some omeprazole capsules contain sugar or lactose (for example the UK Zentiva capsule, UK 4.4). If you have a sugar or lactose intolerance, read the carton or ask us before ordering.
Prescription and legal status
In the US, omeprazole delayed-release capsules for the uses above are prescription medicines ("Rx Only", US label). Omeprazole 20 mg is also sold without a prescription for frequent heartburn, as Prilosec OTC tablets (NDA 021229) and generic and store brand capsules and tablets, for adults, in 14 day courses (Drug Facts labels). Prescription Prilosec capsules (NDA 019810) are discontinued; the FDA's Federal Register determination says they were "not discontinued or withdrawn for safety or effectiveness reasons" (Drugs@FDA). The only prescription Prilosec product still listed as marketed in Drugs@FDA is a delayed-release oral suspension (NDA 022056). The FDA says personal importation of unapproved medicines is illegal in most circumstances.
In the UK, omeprazole 20 mg capsules such as Losec Capsules 20mg and the Zentiva capsule are prescription only medicines (POM) (emc). Small packs for adults with reflux symptoms are on general sale (GSL): Boots One-a-day Acid Reflux Relief 20mg Gastro Resistant Capsules (PL 42807/0005, 7 or 14 capsules) and Pyrocalm Control 20mg tablets (PL 14017/0277, 7 or 14 tablets), each for up to 14 days (emc). In Australia, the Poisons Standard (October 2026) makes oral omeprazole containing 20 mg or less per dosage unit, for heartburn and other reflux symptoms, Schedule 2 (pharmacy medicine) in packs of up to 7 days' supply and Schedule 3 (pharmacist only) up to 14 days' supply; all other omeprazole is Schedule 4 (prescription). healthdirect lists Omeprazole Sandoz enteric capsules as Schedule 4 and PBS listed. In Canada, Losec 20 mg capsules (DIN 00846503) and Apo-Omeprazole 20 mg capsules (DIN 02245058) are marketed prescription drugs, and Apotex's Heartburn Control omeprazole 20 mg capsule (DIN 02435683) is a marketed non-prescription drug (Health Canada). In India, Tata 1mg and Truemeds mark Omez 20 as prescription required. Our 60 to 120 capsule packs are far larger than any non-prescription pack in these countries. Check the rules where you live.
Buying genuine Omez
The MHRA warns that "Any medicine not authorised for sale in the UK can be unsafe or ineffective and there is no way of knowing what is in them or the negative health effects they can have", and it advises UK buyers to "Only use UK-registered pharmacies, including online pharmacies displaying the official green cross logo". That warning covers this Indian Omez pack. When your order arrives, read the strip: it should say Omez 20 and omeprazole 20 mg, name Dr Reddy's Laboratories, and carry a batch number and expiry date. We have not confirmed what the Indian capsule looks like (Dr Reddy's South African Omez 20 is a lavender and grey capsule marked "R158", but that is a different market). These checks cannot prove that capsules are genuine, because counterfeiters copy packaging. If a batch causes unusual symptoms, seek medical advice and report it to your medicines regulator (the MHRA Yellow Card scheme in the UK, FDA MedWatch in the US, the TGA in Australia or Health Canada) as well as to us.
Storage. Truemeds says store Omez 20 below 25°C; Apollo says room temperature, 20°C to 25°C, in the original container away from moisture and light. The US label says store at 20°C to 25°C in a tight container protected from light and moisture (16), and the UK capsule label says store below 25°C in the original package to protect from moisture (6.4). Keeping it below 25°C, dry, in the strip covers all of them (our advice). No refrigeration is needed.
Delivery
We ship Omez 20mg to the US, UK, Australia and Canada in plain packaging with tracking. Standard delivery takes 7 to 14 business days. Shipping costs a flat $25 on orders under $149 and is free from $149. If a doctor has just started you on omeprazole for an ulcer, oesophagitis or H. pylori, do not wait for our delivery: start the course with a local supply (our advice). See our shipping page and refund policy.
Related guides
- Ecosprin 75mg: low-dose aspirin. Aspirin can cause stomach ulcers and bleeding, and the UK omeprazole label lists preventing NSAID-associated ulcers in people at risk; ask your doctor whether you need stomach protection
- Buy Medicine Online Safely: Complete Guide to Secure Online Pharmacy Shopping
Sources
- Omeprazole Delayed-Release Capsules USP 10 mg, 20 mg, 40 mg, US prescribing information and Medication Guide, Dr. Reddy's Laboratories Limited, revised 06/2025 (DailyMed setid 603d2d06-c5e8-4378-a422-8dca1a410af7, SPL version 34, 2 March 2026): sections 1, 2.1 to 2.3, 4, 5.1 to 5.13, 6.1, 7, 8.1, 8.2, 8.4 to 8.7, 10, 12.3, 14.4, 14.5, 16, 17. DailyMed
- Prilosec OTC (omeprazole delayed-release tablets 20 mg) Drug Facts, Procter and Gamble (DailyMed setid 35a79458-79f6-44d6-b74c-b4f4aaf0dde0, 5 October 2026). DailyMed
- Omeprazole delayed-release capsules 20 mg (non-prescription) Drug Facts, Dr. Reddy's Laboratories Limited, ANDA078878 (DailyMed setid 0e8fde83-a55c-edaf-3c66-e1fc77d0bc11). DailyMed
- Drugs@FDA (openFDA), NDA 019810 Prilosec capsules (discontinued) and NDA 021229 Prilosec OTC, checked 31 October 2026. Drugs@FDA
- Omeprazole 20mg gastro-resistant Capsules, UK Summary of Product Characteristics, Zentiva, date of revision 29/08/2025 (emc 15127; legal category Prescription only medicine): sections 4.1 to 4.9, 5.1, 6.3, 6.4. emc
- Losec Capsules 20mg, UK SmPC, Neon Healthcare, revised 12/02/2026 (emc 1509; Prescription only medicine). emc
- Boots One-a-day Acid Reflux Relief 20mg Gastro Resistant Capsules, UK patient leaflet, PL 42807/0005, prepared February 2025 (emc 101415; General Sales List). emc
- Pyrocalm Control 20mg Gastro-Resistant Tablets, UK SmPC, Dexcel Pharma, PL 14017/0277 (emc 9154; General Sales List). emc
- Centers for Medicare and Medicaid Services. NADAC 2026, file as of 28 October 2026, all rows effective 21 October 2026: omeprazole DR 20 mg capsule $0.03045 (35 NDC rows); omeprazole DR 20 mg tablet $0.39142 (19 rows); omeprazole magnesium DR 20 mg capsule $0.38889 (5 rows); omeprazole magnesium DR 20 mg tablet $0.47438 (10 rows). data.medicaid.gov
- Therapeutic Goods (Poisons Standard, October 2026) Instrument 2026, F2026L01327, Schedules 2, 3 and 4 entries for omeprazole. Federal Register of Legislation
- healthdirect Australia: Omeprazole (Sandoz), checked 31 October 2026. healthdirect
- Health Canada Drug Product Database: Losec DIN 00846503, Apo-Omeprazole DIN 02245058, Heartburn Control DIN 02435683; checked 31 October 2026. Health Canada
- Indian pharmacy listings for Omez 20 (Tata 1mg, PharmEasy, Truemeds, Apollo Pharmacy) and Dr Reddy's South Africa Omez 10/20/40 professional information (23 April 2024), checked 31 October 2026.
- MHRA. 20 million illegal erectile dysfunction pills seized as MHRA warns against risky online buys, 13 February 2026. GOV.UK
- Edurant 25 mg film-coated tablets (rilpivirine), UK SmPC, Janssen-Cilag, date of revision 31/03/2026 (emc 4968): sections 4.3 and 4.5. emc
- US Food and Drug Administration. Personal Importation. FDA
This page is for information and is not medical advice. Omeprazole treats acid-related conditions; heartburn with chest pain, trouble swallowing, vomiting blood, black stools or weight loss needs a doctor, not a longer course of omeprazole.
Key Information
- ✓Active Ingredient: Omeprazole
- ✓Category: Digestive Health
- ✓Form: Capsule
- ✓Brand: Omez
- ✓Manufacturer: Dr Reddy's Laboratories Ltd
Frequently Asked Questions
What is Omez 20?
Omez 20 is Dr Reddy's Indian brand of omeprazole 20 mg capsules. Omeprazole is a proton pump inhibitor (PPI) that lowers the amount of acid the stomach makes. Tata 1mg, PharmEasy, Truemeds and Apollo list it as a capsule from Dr Reddy's Laboratories Ltd, in strips of 20 or 30. We sell it in packs of 60, 90 and 120 capsules.
Is Omez 20 the same as Prilosec or US omeprazole?
It has the same active ingredient at the same strength. Dr Reddy's also makes a US generic omeprazole 20 mg capsule, but we have no document showing that Indian Omez 20 uses the same formula, and we have not seen data comparing Omez 20 with Prilosec or any US, UK, Australian or Canadian product. Prescription Prilosec capsules are discontinued in the US; Prilosec OTC is a 20 mg tablet sold without a prescription.
How much does Omez 20mg cost per capsule?
As of October 2026, $0.32 a capsule in the 60 pack and $0.31 in the 90 and 120 packs, before shipping. Shipping is $25 under $149, so a single pack costs $0.52 to $0.73 a capsule with shipping. US pharmacies pay about $0.03 a capsule for generic prescription omeprazole 20 mg (NADAC, effective 21 October 2026), so in the US a local prescription will usually cost less than ours. The pack selector shows the current price.
How do I take Omez 20?
Take one capsule a day before a meal (US label), preferably in the morning with half a glass of water (UK label). Swallow it whole; do not chew or crush it. If you miss a dose, take it as soon as you can unless the next dose is due; never take two doses together. Antacids may be taken with it.
Should I take 10 mg, 20 mg or 40 mg?
20 mg once a day is the label dose for most uses, including reflux symptoms, healing erosive oesophagitis and duodenal ulcer. 10 mg is used to keep healed oesophagitis healed in some people (the UK long-term dose, and the US dose for people with liver impairment or of Asian descent). 40 mg is for gastric ulcer (US) or ulcers and oesophagitis that respond poorly (UK), and only on a doctor's advice. In a US study, 40 mg was not superior to 20 mg for healing oesophagitis.
How long can I take omeprazole 20 mg?
For heartburn you treat yourself, the US and UK non-prescription labels allow 14 days; the US label says not more often than every 4 months unless a doctor directs. On a doctor's advice, the US label gives up to 4 weeks for reflux symptoms and 4 to 8 weeks to heal oesophagitis. The UK label says symptoms not controlled after 4 weeks of 20 mg need further investigation, and long-term users should be kept under regular review. Our smallest pack is 60 capsules, which is two months at one a day.
Is long-term omeprazole use safe?
The labels warn about risks that are linked to long courses or high doses: C. difficile diarrhoea, fractures of the hip, wrist or spine, low magnesium (usually after a year), vitamin B12 deficiency (for example after more than 3 years), fundic gland polyps (especially after a year), lupus and kidney inflammation. The US label says use the lowest dose and shortest duration appropriate to the condition. If you take it for months, review the need with your doctor.
What are the side effects of Omez 20?
In clinical trials of omeprazole capsules, the most common were headache (7%), abdominal pain (5%), nausea (4%), diarrhoea (4%), vomiting (3%) and flatulence (3%) (US label). Get help straight away for chest pain that could be your heart, vomiting blood or black stools, allergic swelling or breathing problems, a blistering rash, severe watery diarrhoea with fever, much less urine or blood in the urine, or seizures.
Who should not take Omez 20?
Never take it if you are allergic to omeprazole, any capsule ingredient or any substituted benzimidazole (the US Medication Guide adds any other PPI), or if you take rilpivirine (US omeprazole label; the UK rilpivirine label also says it must not be combined with PPIs) or nelfinavir (UK label). The US label says avoid it with clopidogrel, St John's wort, rifampin, atazanavir and nelfinavir; the UK label discourages clopidogrel and does not recommend atazanavir. People on warfarin, citalopram, cilostazol, phenytoin, tacrolimus, digoxin or high-dose methotrexate need their doctor's advice first.
Do I need a prescription for omeprazole 20 mg?
It depends on the pack. In the US, omeprazole 20 mg capsules for ulcers and GERD are prescription only, while 14 day heartburn packs are sold without one. In the UK most 20 mg capsules are prescription only, but small 7 or 14 capsule packs are on general sale. In Australia, packs up to 7 days are pharmacy medicines, up to 14 days pharmacist only, and the rest prescription. In Canada there are prescription and non-prescription 20 mg capsules. Tata 1mg and Truemeds mark Omez 20 as prescription in India. This Indian pack is not registered with the FDA, MHRA, TGA or Health Canada.
How long does delivery of Omez 20mg take?
Orders usually arrive in 7 to 14 business days in plain packaging, with tracking. Shipping is $25 on orders under $149 and free from $149. If a doctor has just started you on omeprazole for an ulcer or H. pylori, start the course with a local supply rather than waiting for our delivery.
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