Tobramycin Eye Drops and Tobradex: Dosage, Side Effects, Steroid Warnings and US Cost

Tobramycin eye drops (tobramycin ophthalmic solution 0.3%, first sold in the US as Tobrex) are a prescription aminoglycoside antibiotic for bacterial infections of the outer eye and eyelids. Tobradex adds a steroid, dexamethasone, to the same antibiotic. The two look alike on a pharmacy shelf but they are prescribed for different problems and carry very different warnings. This guide covers what the US labels say about each: what they treat, the dose, side effects, the steroid warnings on Tobradex, Tobradex ST and Zylet, use in pregnancy and in children, contact lenses, how tobramycin compares with fluoroquinolone drops, which brands are still on the US market, and what a bottle costs US pharmacies.

Every dose, warning and number below comes from current US labels on DailyMed, Drugs@FDA records via openFDA and the CMS NADAC price survey, all opened on 4 November 2026 (sources at the end of this page). Your prescriber may set a different schedule; follow the prescription.

Tobramycin eye drops at a glance

Item	Tobramycin 0.3% (Tobrex type)	Tobramycin with dexamethasone (Tobradex type)
Active ingredients	Tobramycin 3 mg per mL (0.3%)	Tobramycin 3 mg and dexamethasone 1 mg per mL (0.3%/0.1%); Tobradex ST has 0.5 mg dexamethasone per mL (0.05%)
Form	Solution (drops) or 0.3% eye ointment	Suspension (shake well) or eye ointment
Labeled use	External infections of the eye and its adnexa caused by susceptible bacteria	Steroid-responsive inflammatory eye conditions where superficial bacterial infection, or a risk of it, exists
Usual drop dose	1 or 2 drops every 4 hours (mild to moderate)	1 or 2 drops every 4 to 6 hours
Contraindications	Known hypersensitivity to any component	Epithelial herpes simplex keratitis (dendritic keratitis), vaccinia, varicella and many other viral diseases of the cornea and conjunctiva; mycobacterial and fungal eye infections; hypersensitivity
Youngest labeled age	2 months	2 years
Preservative	Benzalkonium chloride 0.01% (drops)	Benzalkonium chloride 0.01% (suspension)
Status	Prescription only in the US	Prescription only in the US

What tobramycin eye drops treat

The tobramycin 0.3% solution and Tobrex ointment labels have one indication: "external infections of the eye and its adnexa caused by susceptible bacteria." The adnexa are the eyelids, tear system and surrounding tissues. In practice that usually means bacterial conjunctivitis (pink eye) and eyelid infections such as blepharitis, as judged by a clinician. The label adds that "appropriate monitoring of bacterial response to topical antibiotic therapy should accompany" its use.

In laboratory studies, the labels list tobramycin as active against susceptible strains of:

• Staphylococci, including S. aureus and S. epidermidis, including penicillin-resistant strains.
• Streptococci, including some Group A beta-hemolytic species, some nonhemolytic species and some Streptococcus pneumoniae.
• Gram-negative bacteria: Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, Enterobacter aerogenes, Proteus mirabilis, Morganella morganii, most Proteus vulgaris strains, Haemophilus influenzae and H. aegyptius, Moraxella lacunata, Acinetobacter calcoaceticus and some Neisseria species.

The label also notes that in some cases bacteria resistant to gentamicin, another aminoglycoside, remain susceptible to tobramycin. Tobramycin does nothing for viral, fungal or allergic eye problems.

Tobramycin is an aminoglycoside: what that means

Tobramycin belongs to the aminoglycoside family, the same group as gentamicin. Aminoglycosides stop bacteria making the proteins they need to grow. That makes tobramycin a different class from the fluoroquinolone eye drops (ofloxacin, ciprofloxacin, moxifloxacin), which block bacterial DNA enzymes.

Three label points follow from the class:

• Cross-sensitivity: "Cross-sensitivity to other aminoglycoside antibiotics may occur." If you have reacted to another aminoglycoside, such as gentamicin, tell your prescriber before using tobramycin.
• Systemic aminoglycoside effects: the label notes that neurotoxicity, ototoxicity (hearing and balance damage) and nephrotoxicity (kidney damage) have occurred in patients receiving systemic aminoglycoside therapy, meaning injections or infusions. These are listed as reports with systemic use, not with eye drops.
• Muscle weakness disorders: aminoglycosides "may aggravate muscle weakness in patients with known or suspected neuromuscular disorders, such as myasthenia gravis or Parkinson's disease." Mention either condition to your prescriber.

Do you need antibiotic eye drops for pink eye?

Often not. Pink eye can be viral, bacterial or allergic, and many bacterial cases settle on their own. A 2023 Cochrane review included 21 randomized trials with 8,805 participants. In the pooled trials that reported clinical cure, 55.5% (408 of 735) on placebo had clinical resolution by days 4 to 9, against 68.2% (504 of 739) on an antibiotic. Our antibiotic eye drops guide covers when pink eye is likely to need an antibiotic and how the classes compare. This page stays with tobramycin and its steroid combinations.

Tobramycin eye drops dosage

Product (US label)	Mild to moderate infection	Severe infection
Tobramycin 0.3% solution	1 or 2 drops into the affected eye(s) every 4 hours	2 drops hourly until improvement, then reduce before stopping
Tobrex 0.3% ointment	A half-inch ribbon into the affected eye(s) 2 or 3 times per day	A half-inch ribbon every 3 to 4 hours until improvement, then reduce before stopping

The tobramycin labels do not set a fixed number of days. Your prescriber decides how long to continue, and the label's wording means the dose is reduced as the eye improves rather than stopped abruptly. If the eye is no better after a few days, go back to the prescriber rather than continuing on your own.

How to use the drops and the ointment

1. Wash your hands. Take out contact lenses (see the contact lens section).
2. Tilt your head back and pull the lower lid down gently to make a small pocket.
3. Drops: hold the bottle over the eye and squeeze one drop into the pocket. Shake a suspension (Tobradex type) well first.
4. Ointment: the Tobrex label says to place about half an inch of ointment in the "V" pocket, then look downward before closing your eye.
5. Do not let the dropper or tube tip touch the eye, your fingers or any surface; the labels say this can contaminate the contents.
6. If you use other eye medicines too, ask your pharmacist how far apart to space them.

Use a separate bottle for each person, and do not keep an opened bottle to treat a future red eye.

Tobramycin eye drops side effects

The tobramycin labels give no table of rates by event. They say the most frequent adverse reactions are hypersensitivity and localized ocular toxicity, including lid itching and swelling and conjunctival redness (erythema), and that these occur in "less than three of 100 patients" treated with the 0.3% solution. The combination labels describe the same tobramycin reactions as occurring in less than 4% of patients.

Source of the report	Events listed on the US label
Most frequent (tobramycin)	Lid itching and swelling, conjunctival redness; under 3 in 100 patients
Postmarketing (tobramycin solution and ointment)	Anaphylactic reaction, Stevens-Johnson syndrome, erythema multiforme
Steroid component (Tobradex type)	Raised eye pressure with possible glaucoma and infrequent optic nerve damage, posterior subcapsular cataract, delayed wound healing
Tobradex ST, outside the eye	Headache and increased blood pressure, 0.5% to 1%
Dexamethasone component	Cushing's syndrome and adrenal suppression after use in excess of the listed dosing in predisposed patients, including children and people taking CYP3A4 inhibitors

Increasing pain, worsening redness, or blurred vision that does not clear should be checked.

Allergic reactions: when to stop

The labels warn that sensitivity to topically applied aminoglycosides may occur, and that severity "may vary from local effects to generalized reactions such as erythema, itching, urticaria, skin rash, anaphylaxis, anaphylactoid reactions, or bullous reactions." If a sensitivity reaction occurs, the label says to discontinue use. A rash, hives, blistering, or swelling of the face or throat with trouble breathing needs emergency help.

Both tobramycin products also state "NOT FOR INJECTION INTO THE EYE." They are for the eye surface only.

Long use and resistant organisms

"As with other antibiotic preparations, prolonged use may result in overgrowth of nonsusceptible organisms, including fungi. If superinfection occurs, appropriate therapy should be initiated." The Tobrex ointment label adds that ophthalmic ointments may retard corneal wound healing. An eye that is getting worse on tobramycin may have an infection the drug does not cover, and needs to be examined again.

Tobradex: what the steroid combination is for

Tobradex is not a stronger tobramycin. It is labeled for a different situation: "steroid-responsive inflammatory ocular conditions for which a corticosteroid is indicated and where superficial bacterial ocular infection or a risk of bacterial ocular infection exists." The label lists inflammatory conditions of the conjunctiva, cornea and front segment of the eye, chronic anterior uveitis, and corneal injury from chemical, radiation or thermal burns or penetrating foreign bodies. The antibiotic is added "where the risk of superficial ocular infection is high or where there is an expectation that potentially dangerous numbers of bacteria will be present in the eye."

The labels say the steroid suppresses inflammation but may "delay or slow healing" and may inhibit the body's defence against infection. That is why a plain red, sticky eye is usually a case for an antibiotic alone, and a steroid combination is a decision for a clinician who has examined the eye.

Tobradex and Tobradex ST dosage

Product	Dose on the US label	Prescribing limit on the label
Tobramycin/dexamethasone 0.3%/0.1% suspension (Tobradex and generics)	1 or 2 drops every 4 to 6 hours; for the first 24 to 48 hours up to 1 or 2 drops every 2 hours; reduce gradually as signs improve	Not more than 20 mL initially; no refill without further evaluation
Tobradex ointment	About a half-inch ribbon up to 3 or 4 times daily	Not more than 8 g initially
Tobradex ST 0.3%/0.05% suspension	1 drop every 4 to 6 hours; for the first 24 to 48 hours up to 1 drop every 2 hours; shake well	Not more than one bottle initially
Zylet (loteprednol 0.5%/tobramycin 0.3%)	1 or 2 drops every 4 to 6 hours; for the first 24 to 48 hours up to every 1 to 2 hours	Not more than 20 mL initially

The Tobradex suspension, Tobradex ST and Zylet labels say care should be taken not to discontinue therapy prematurely, and the frequency should be decreased gradually; the Tobradex ointment label gives no tapering instruction. The Tobradex ST label also tells prescribers to check eye pressure before the first prescription and before each renewal, and to re-evaluate the patient if signs and symptoms fail to improve after 2 days.

Tobradex warnings: eye pressure, cataract, healing and infections

These are the label warnings that set a steroid combination apart from plain tobramycin:

• Contraindicated in epithelial herpes simplex keratitis (dendritic keratitis), vaccinia, varicella and many other viral diseases of the cornea and conjunctiva; in mycobacterial infection of the eye; in fungal diseases of ocular structures; and with hypersensitivity to a component.
• Glaucoma: "Prolonged use of steroids may result in glaucoma, with damage to the optic nerve, defects in visual acuity and fields of vision." The Tobradex suspension label says intraocular pressure "should be routinely monitored even though it may be difficult in pediatric patients and uncooperative patients." The Tobradex ST and Zylet labels say pressure should be monitored if the product is used for 10 days or longer.
• Cataract: steroid use may result in posterior subcapsular cataract formation.
• Delayed healing: steroids after cataract surgery may delay healing and increase the incidence of bleb formation. In diseases that thin the cornea or sclera, perforations have been known to occur.
• Masked or worse infection: prolonged use may suppress the host response and increase the hazard of secondary eye infections. In acute purulent (pus-forming) conditions, steroids may mask infection or enhance existing infection.
• Viral infection: the Tobradex ST label says use in people with a history of herpes simplex "requires great caution," and that ocular steroids may prolong the course and worsen many viral eye infections.
• Fungal infection: fungal infections of the cornea are particularly prone to develop with long-term local steroid use. Fungal invasion must be considered in any persistent corneal ulcer where a steroid has been used.
• Blurred vision: Tobradex ST may blur vision for a while after dosing; take care driving or operating machinery.

Because a viral or fungal eye infection can look like a bacterial one, the Tobradex ST and Zylet labels say the first prescription and any renewal should come only after an eye examination with magnification, such as a slit lamp, and fluorescein staining where appropriate.

How often steroid eye drops raise eye pressure

The Tobradex and Tobradex ST labels describe the pressure risk but give no rate. The Zylet label (loteprednol with tobramycin) gives two sets of numbers. They are separate studies, so they should not be read as a comparison of Zylet with Tobradex.

Zylet 42-day safety study	Zylet	Placebo
Increased intraocular pressure	10%	4%
Burning and stinging on instillation	9%	Not stated
Injection (redness), approximately	20%	Not stated
Superficial punctate keratitis, approximately	15%	Not stated
Headache (non-ocular)	About 14%	Not stated

Pooled studies of 28 days or longer (Zylet label)	Rise of 10 mm Hg or more
Prednisolone acetate 1%	7% (11 of 164)
Loteprednol etabonate	2% (15 of 901)
Placebo	0.5% (3 of 583)

The pooled figures cover loteprednol and prednisolone, not dexamethasone, and they come from courses of 28 days or more. They show why every steroid eye drop label asks for pressure checks on longer use. No label we opened gives an equivalent number for Tobradex.

Tobradex vs Tobradex ST vs Zylet

Item	Tobradex suspension	Tobradex ST	Zylet
Steroid	Dexamethasone 0.1%	Dexamethasone 0.05%	Loteprednol etabonate 0.5%
Antibiotic	Tobramycin 0.3%	Tobramycin 0.3%	Tobramycin 0.3%
Extra inactives	Hydroxyethyl cellulose, tyloxapol	Xanthan gum, propylene glycol, tyloxapol	Glycerin, povidone, tyloxapol
Dose	1 or 2 drops every 4 to 6 hours	1 drop every 4 to 6 hours	1 or 2 drops every 4 to 6 hours
Children	Not established below 2 years	Not established below 2 years	Two trials in ages 0 to 6 did not show efficacy over vehicle
US generic	Yes (rated AB)	None listed	Yes (rated AB)

The Tobradex ST label reports that in cataract surgery patients, dexamethasone levels in the eye's aqueous humor after Tobradex ST were similar to those after Tobradex, with a mean peak of 33.7 ng/mL 2 hours after one dose. No label compares the clinical results of the three products.

How much reaches the blood

For tobramycin, the labels say no data are available on the extent of systemic absorption from the eye products, though some systemic absorption can occur with eye medicines. For dexamethasone, the one study on the label found very low levels: after Tobradex 4 times a day for 2 days in both eyes of healthy volunteers, peak plasma dexamethasone concentrations were less than 1 ng/mL. The dexamethasone warning about Cushing's syndrome and adrenal suppression applies to use beyond the listed dose, particularly in children and people taking CYP3A4 inhibitors.

Contact lenses

The plain tobramycin solution label says patients should be advised not to wear contact lenses if they have signs and symptoms of bacterial eye infection. The Tobradex suspension and Tobradex ST labels go further: "Contact lenses should not be worn during the use of this product." Tobradex ST explains that it contains benzalkonium chloride, which may be absorbed by soft contact lenses; Zylet gives the same advice for soft lenses. A red, painful eye in a contact lens wearer can be a corneal infection rather than conjunctivitis and needs an eye examination the same day.

Pregnancy and breastfeeding

Tobramycin alone. The label says reproduction studies in three types of animals at doses up to 33 times the normal human systemic dose showed no evidence of impaired fertility or harm to the fetus. "There are, however, no adequate and well-controlled studies in pregnant women," so the drug "should be used during pregnancy only if clearly needed." For nursing mothers, the label says a decision should be made whether to discontinue nursing or the drug, taking into account the importance of the drug to the mother.

Tobradex type. The steroid adds caution. The label says corticosteroids have been teratogenic in animal studies, and that ocular 0.1% dexamethasone resulted in a 15.6% and 32.3% incidence of fetal anomalies in two groups of pregnant rabbits. Prolonged or repeated corticoid use in pregnancy has been associated with an increased risk of intra-uterine growth retardation. The product "should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus," and infants born to mothers who received substantial doses of corticosteroids should be watched for signs of hypoadrenalism. For breastfeeding, the label says caution should be exercised. Tell your prescriber if you are pregnant or breastfeeding.

Children and older adults

• Tobramycin solution and Tobrex ointment: the label says clinical studies have shown tobramycin to be safe and effective for use in children, but safety and effectiveness below the age of 2 months has not been established.
• Tobradex suspension, Tobradex ointment and Tobradex ST: safety and effectiveness below the age of 2 years have not been established.
• Zylet: two trials in children aged 0 to 6 years (lid inflammation and blepharoconjunctivitis) did not show efficacy compared with vehicle, with no differences in safety.
• Older adults: all the labels say no overall differences in safety or effectiveness have been observed between elderly and younger patients.

Any newborn with red or sticky eyes needs to be seen by a doctor before any drops are used.

Tobramycin vs ofloxacin, ciprofloxacin and moxifloxacin eye drops

Drop (US label)	Class	Conjunctivitis dose	Youngest labeled age	Corneal ulcer dose on label
Tobramycin 0.3%	Aminoglycoside	1 or 2 drops every 4 hours; severe: 2 drops hourly until improvement	2 months	No
Ofloxacin 0.3% (Ocuflox)	Fluoroquinolone	1 to 2 drops every 2 to 4 hours on days 1 and 2, then 4 times daily on days 3 to 7	1 year	Yes
Ciprofloxacin 0.3%	Fluoroquinolone	1 or 2 drops every 2 hours while awake for 2 days, then every 4 hours while awake for 5 days	All ages	Yes
Moxifloxacin 0.5% (Vigamox)	Fluoroquinolone	1 drop 3 times a day for 7 days	All ages, including neonates	No

No trial on these labels compares tobramycin with a fluoroquinolone drop head to head, so the table is not a ranking. The practical differences are the class (useful if you are allergic to one class), the labeled ages, and the schedule. Tobramycin is also the antibiotic in the US steroid combinations (Tobradex, Tobradex ST, Zylet); ofloxacin and ciprofloxacin are the fluoroquinolone drops with a US corneal ulcer dose. Our ofloxacin eye drops guide and moxifloxacin eye drops guide cover those drugs in detail, and the prescription eye drops guide maps the other eye drop classes.

Which tobramycin eye products are still sold in the US

Drugs@FDA, queried through openFDA on 4 November 2026, lists these tobramycin eye products:

Product	Application, first approval	Status on Drugs@FDA
Tobrex 0.3% solution (Novartis)	NDA 050541, 12 December 1980	Discontinued; FDA noted a Federal Register determination that it was not discontinued or withdrawn for safety or effectiveness reasons
Tobrex 0.3% ointment (Novartis)	NDA 050555, 25 November 1981	Prescription
Generic tobramycin 0.3% solution	6 applications: Alembic, Bausch and Lomb, Chartwell, Gland, Sandoz (sold as Tobrex), Somerset	Prescription, rated AT; Aktob, Apotex and Alcon generics discontinued
Tobradex suspension (now held by Sandoz)	NDA 050592, 18 August 1988	Prescription
Tobradex ointment (Novartis)	NDA 050616, 28 September 1988	Prescription
Generic tobramycin/dexamethasone suspension	Bausch and Lomb, Padagis; Sandoz sells one under the Tobradex application	Prescription, rated AB; Amneal generic discontinued
Tobradex ST (Harrow Eye)	NDA 050818, 13 February 2009	Prescription; no generic listed
Zylet (Bausch and Lomb)	NDA 050804, 14 December 2004	Prescription; Alembic generic (ANDA 217597) approved 10 December 2025
Tobrasone (tobramycin with fluorometholone acetate)	NDA 050628, 21 July 1989	Discontinued

So if you are told Tobrex drops are discontinued, that is correct for the original Novartis application, but generic tobramycin 0.3% drops are widely available. No tobramycin eye product on Drugs@FDA has an over-the-counter status.

What tobramycin eye drops cost in the US

The CMS National Average Drug Acquisition Cost (NADAC) survey records what US retail pharmacies pay for a medicine, not the price at the counter. Prices below are the NADAC per mL or per gram in the file dated 4 November 2026, multiplied by a US label package size.

Product	NADAC	Package	Cost per package
Tobramycin 0.3% eye drops (generic)	$1.09593 per mL	5 mL	$5.48
Ofloxacin 0.3% eye drops (generic)	$1.22968 per mL	5 mL	$6.15
Ciprofloxacin 0.3% eye drops (generic)	$1.47777 per mL	5 mL	$7.39
Tobramycin/dexamethasone suspension (generic)	$4.28732 per mL	5 mL	$21.44
Loteprednol/tobramycin (generic)	$39.46335 per mL	5 mL	$197.32
Tobradex ST	$46.62789 per mL	5 mL	$233.14
Tobrex 0.3% eye ointment	$84.33326 per g	3.5 g	$295.17
Tobradex eye ointment	$89.67612 per g	3.5 g	$313.87
Zylet	$64.40924 per mL	5 mL	$322.05

The gap is large. A generic tobramycin bottle and a generic tobramycin/dexamethasone bottle cost pharmacies a few dollars to about $21, while the brand ointments, Tobradex ST and Zylet cost hundreds. The NADAC file has no current entry for brand Tobradex suspension. Insurance, discount cards and pharmacy markups change what you pay.

Our Toba, Toba DM and Toba F listings

We list three Sun Pharma eye drops sold in India. They are not FDA approved products, and the US labels above do not transfer to them automatically. All three are prescription medicines: in the US, tobramycin and tobramycin combination eye products are prescription only, and Indian pharmacy listings show Toba DM and Toba F as prescription required.

Product	Composition	Bottle	Pack	Price	Per bottle
Toba Eye Drop	Tobramycin 0.3% (3 mg per mL)	5 mL	3 bottles	$13.00	$4.33
Toba Eye Drop	Tobramycin 0.3%	5 mL	6 bottles	$23.00	$3.83
Toba Eye Drop	Tobramycin 0.3%	5 mL	12 bottles	$43.00	$3.58
Toba DM Eye Drop	Tobramycin 0.3% with dexamethasone 0.1%	10 mL	3 bottles	$8.00	$2.67
Toba DM Eye Drop	Tobramycin 0.3% with dexamethasone 0.1%	10 mL	6 bottles	$15.00	$2.50
Toba DM Eye Drop	Tobramycin 0.3% with dexamethasone 0.1%	10 mL	12 bottles	$29.00	$2.42
Toba F Eye Drop	Tobramycin 0.3% with fluorometholone 0.1%	5 mL	3 bottles	$20.00	$6.67
Toba F Eye Drop	Tobramycin 0.3% with fluorometholone 0.1%	5 mL	6 bottles	$35.00	$5.83
Toba F Eye Drop	Tobramycin 0.3% with fluorometholone 0.1%	5 mL	12 bottles	$59.00	$4.92

Prices are from our product listings as of 4 November 2026, before shipping. Compositions for Toba DM and Toba F are as given by the Indian pharmacy listings on 1mg and Apollo Pharmacy; check the carton when the pack arrives.

Two points matter. First, Toba DM is listed on 1mg as a 10 mL "ophthalmic solution," while US tobramycin/dexamethasone is a suspension that must be shaken; the strengths match Tobradex but the formulation is not the same product. Second, Toba F contains fluorometholone, a different steroid from dexamethasone. There is no tobramycin and fluorometholone product currently marketed in the US (Tobrasone is discontinued), so no current US label covers it. Both combinations carry the steroid risks described above and should be used only on a prescriber's instructions after an eye examination.

Our shipping page lists standard registered shipping at a $25 flat rate, free on orders of $149 or more, with delivery in 7 to 14 business days to the US. The smallest Toba order therefore costs $38.00 delivered, against about $5.48 that a US pharmacy pays for one generic tobramycin bottle. An eye infection needs treatment within days, not weeks. For one infection, a US prescription filled locally is faster and usually cheaper. A multi-bottle pack is also more than a labeled course; please do not keep spare bottles to treat future red eyes, and never use a leftover steroid combination on an undiagnosed eye.

Importing eye drops into the US

The FDA's personal importation page says: "In most circumstances, it is illegal for individuals to import drugs or devices into the U.S. for personal use" and "If a drug is approved for use in another country but is an unapproved new drug in the U.S. it is illegal to import." The same page describes limited situations in which FDA personnel may consider a more permissive decision. Check your own situation before ordering. Our guide to eye drop recalls and checking your bottle explains what to look at when a bottle arrives.

When to see a doctor about an eye problem

• Eye pain, blurred vision that does not clear with blinking, strong sensitivity to light, or a white spot on the clear front of the eye: these can be signs of a corneal infection and need same-day eye care.
• Any red, painful eye in a contact lens wearer.
• A newborn with red or sticky eyes.
• A rash, hives, blistering, swelling of the face or throat, or trouble breathing after a dose: stop and get emergency help.
• No improvement after 2 days on a steroid combination, or a worsening eye on any tobramycin product.
• A history of herpes eye infection, glaucoma or cataract, before anyone starts a steroid eye drop.
• Use of a steroid combination for 10 days or more: ask about an eye pressure check.

Sources

• Tobramycin ophthalmic solution USP 0.3%, Somerset Therapeutics, US prescribing information, revised July 2024. DailyMed
• Tobramycin ophthalmic solution USP 0.3%, Alembic, US prescribing information. DailyMed
• TOBREX (tobramycin ophthalmic ointment) 0.3%, Novartis, US prescribing information. DailyMed
• Tobramycin and dexamethasone ophthalmic suspension 0.3%/0.1%, Sandoz (Tobradex application), US prescribing information, revised October 2024. DailyMed
• Tobramycin and dexamethasone ophthalmic suspension, Bausch and Lomb and Padagis, US prescribing information. DailyMed (Bausch), DailyMed (Padagis)
• TOBRADEX (tobramycin and dexamethasone ophthalmic ointment), Novartis, US prescribing information. DailyMed
• TOBRADEX ST (tobramycin and dexamethasone ophthalmic suspension) 0.3%/0.05%, Harrow Eye, US prescribing information. DailyMed
• ZYLET (loteprednol etabonate and tobramycin ophthalmic suspension) 0.5%/0.3%, Bausch and Lomb, US prescribing information. DailyMed
• OCUFLOX (ofloxacin ophthalmic solution) 0.3%, VIGAMOX (moxifloxacin ophthalmic solution) 0.5% and ciprofloxacin ophthalmic solution 0.3% (Advagen), US prescribing information. Ocuflox, Vigamox, ciprofloxacin
• US Food and Drug Administration, Drugs@FDA via openFDA: tobramycin applications, queried 4 November 2026. Drugs@FDA
• Chen YY, et al. Antibiotics versus placebo for acute bacterial conjunctivitis. Cochrane Database Syst Rev. 2023. PMID 36912752. PubMed
• Centers for Medicare and Medicaid Services, National Average Drug Acquisition Cost (NADAC) 2026, file dated 4 November 2026. data.medicaid.gov
• Toba DM and Toba F product listings, Tata 1mg and Apollo Pharmacy, opened 4 November 2026. Toba DM (1mg), Toba F (1mg), Toba F (Apollo)
• US Food and Drug Administration, Personal Importation. FDA

This page is for information and is not medical advice. Tobramycin and tobramycin with steroid eye products are prescription medicines; a clinician should examine the eye and set your treatment.